Kaposi's Sarcoma Herpesvirus Upregulates Aurora A Expression to Promote p53 Phosphorylation and Ubiquitylation

Aberrant expression of Aurora A kinase has been frequently implicated in many cancers and contributes to chromosome instability and phosphorylation-mediated ubiquitylation and degradation of p53 for tumorigenesis. Previous studies showed that p53 is degraded by Kaposi's sarcoma herpesvirus (KSH...

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Autors principals: Cai, Qiliang, Xiao, Bingyi, Si, Huaxin, Cervini, Amanda, Gao, Jianming, Lu, Jie, Upadhyay, Santosh K., Verma, Suhbash C., Robertson, Erle S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291660/
https://ncbi.nlm.nih.gov/pubmed/22396649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002566
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