Ten novel mutations in the erythroid transcription factor KLF1 gene associated with increased fetal hemoglobin levels in adults

We investigated whether mutations in the KLF1 gene are associated with increased Hb F levels in ethnically diverse patients referred to our laboratory for hemoglobinopathy investigation. Functionally effective KLF1 mutations were identified in 11 out of 131 adult samples with an elevated Hb F level...

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Bibliographic Details
Main Authors: Gallienne, Alice E., Dréau, Hélène M.P., Schuh, Anna, Old, John M., Henderson, Shirley
Format: Artigo
Language:Inglês
Published: Ferrata Storti Foundation 2012
Subjects:
Original Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291586/
https://ncbi.nlm.nih.gov/pubmed/22102705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.055442
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