ANALYSIS OF SITE-SPECIFIC MUTATIONS ON EGFRVIII PHOSPHOTYROSINE SIGNALING NETWORK IDENTIFIES DETERMINANTS GOVERNING U87MG GLIOBLASTOMA CELL GROWTH

To evaluate the role of individual EGFR phosphorylation sites in activating components of the cellular signaling network we have performed a mass spectrometry-based analysis of the phosphotyrosine network downstream of site-specific EGFRvIII mutants, enabling quantification of network-level effects...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Huang, Paul H., Miraldi, Emily R., Xu, Alexander M., Kundukulam, Vibin A., Del Rosario, Amanda M., Flynn, Ryan A., Cavenee, Webster K., Furnari, Frank B., White, Forest M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291333/
https://ncbi.nlm.nih.gov/pubmed/20461251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c001196g
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