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ANALYSIS OF SITE-SPECIFIC MUTATIONS ON EGFRVIII PHOSPHOTYROSINE SIGNALING NETWORK IDENTIFIES DETERMINANTS GOVERNING U87MG GLIOBLASTOMA CELL GROWTH
To evaluate the role of individual EGFR phosphorylation sites in activating components of the cellular signaling network we have performed a mass spectrometry-based analysis of the phosphotyrosine network downstream of site-specific EGFRvIII mutants, enabling quantification of network-level effects...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3291333/ https://ncbi.nlm.nih.gov/pubmed/20461251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c001196g |
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