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Nitrated oleic acid up-regulates PPARγ and attenuates experimental inflammatory bowel disease

Nitric oxide and its metabolites undergo nitration reactions with unsaturated fatty acids during oxidative inflammatory conditions, forming electrophilic nitro-fatty acid derivatives. These endogenous electrophilic mediators activate anti-inflammatory signaling reactions, serving as high-affinity li...

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Detalhes bibliográficos
Main Authors: Borniquel, Sara, Jansson, Emmelie Å., Cole, Marsha P., Freeman, Bruce A., Lundberg, Jon O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290869/
https://ncbi.nlm.nih.gov/pubmed/19932165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.11.014
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