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A Phase II Study of Pegylated Interferon Alfa-2b (PEG-Intron®) in Children with Diffuse Intrinsic Pontine Glioma (DIPG)

BACKGROUND: Interferon-alpha is a cytokine with demonstrated activity in patients with supratentorial gliomas, but the ideal dose and schedule of administration is unknown. Studies suggest low-dose continuous exposure is more efficacious than intermittent high doses. We performed a Phase II study of...

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Détails bibliographiques
Auteurs principaux: Warren, Katherine E., Bent, Robyn, Wolters, Pamela L., Prager, Alisa, Hanson, Ryan, Packer, Roger, Shih, Joanna, Camphausen, Kevin
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290731/
https://ncbi.nlm.nih.gov/pubmed/22086404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26659
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