Nanoresonator Chip-Based RNA Sensor Strategy for Detection of Circulating Tumor Cells: Response using PCA3 as a Prostate Cancer Marker

There is widespread interest in circulating tumor cells (CTCs) in blood. Direct detection of CTCs (often < 1/ml) is complicated by a number of factors, but the presence of ~10(3) to 10(4) copies of target RNA per CTC, coupled with simple enrichments, can greatly increase detection capability. Her...

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Autori principali: Sioss, James A., Bhiladvala, Rustom, Pan, Weihua, Li, Mingwei, Patrick, Susan, Xin, Ping, Dean, Stacey L., Keating, Christine D., Mayer, Theresa S., Clawson, Gary A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290699/
https://ncbi.nlm.nih.gov/pubmed/22115599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2011.11.009
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