Marked Reduction of AKT1 Expression and Deregulation of AKT1-Associated Pathways in Peripheral Blood Mononuclear Cells of Schizophrenia Patients

BACKGROUND: Recent studies have suggested that deregulated AKT1 signaling is associated with schizophrenia. We hypothesized that if this is indeed the case, we should observe both decreased AKT1 expression as well as deregulation of AKT1 regulated pathways in Peripheral Blood Mononuclear Cells (PBMC...

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Main Authors: van Beveren, Nico J. M., Buitendijk, Gabrielle H. S., Swagemakers, Sigrid, Krab, Lianne C., Röder, Christian, de Haan, Lieuwe, van der Spek, Peter, Elgersma, Ype
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290567/
https://ncbi.nlm.nih.gov/pubmed/22393424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032618
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