Marked Reduction of AKT1 Expression and Deregulation of AKT1-Associated Pathways in Peripheral Blood Mononuclear Cells of Schizophrenia Patients

BACKGROUND: Recent studies have suggested that deregulated AKT1 signaling is associated with schizophrenia. We hypothesized that if this is indeed the case, we should observe both decreased AKT1 expression as well as deregulation of AKT1 regulated pathways in Peripheral Blood Mononuclear Cells (PBMC...

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Detalhes bibliográficos
Main Authors: van Beveren, Nico J. M., Buitendijk, Gabrielle H. S., Swagemakers, Sigrid, Krab, Lianne C., Röder, Christian, de Haan, Lieuwe, van der Spek, Peter, Elgersma, Ype
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290567/
https://ncbi.nlm.nih.gov/pubmed/22393424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032618
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