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Probabilistic Inference for Nucleosome Positioning with MNase-Based or Sonicated Short-Read Data

We describe a model-based method, PING, for predicting nucleosome positions in MNase-Seq and MNase- or sonicated-ChIP-Seq data. PING compares favorably to NPS and TemplateFilter in scalability, accuracy and robustness to low read density. To demonstrate that PING predictions from widely available so...

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Détails bibliographiques
Auteurs principaux: Zhang, Xuekui, Robertson, Gordon, Woo, Sangsoon, Hoffman, Brad G., Gottardo, Raphael
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290535/
https://ncbi.nlm.nih.gov/pubmed/22393380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032095
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