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A DIRECTED APPROACH FOR ENGINEERING CONDITIONAL PROTEIN STABILITY USING BIOLOGICALLY SILENT SMALL MOLECULES*

The ability to regulate the function of specific proteins using cell-permeable molecules can be a powerful method for interrogating biological systems. To bring this type of “chemical genetic” control to a wide range of proteins, we recently developed an experimental system in which the stability of...

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Autors principals: Maynard-Smith, Lystranne A., Chen, Ling-chun, Banaszynski, Laura A., Lisa Ooi, A. G., Wandless, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290522/
https://ncbi.nlm.nih.gov/pubmed/17603093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M703902200
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