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Two distinct human DNA diesterases that hydrolyze 3'-blocking deoxyribose fragments from oxidized DNA.

Mammalian cells were investigated for enzymes that help correct oxidative damages in DNA. We focused on 3'-repair diesterases, which process DNA ends at oxidative strand breaks by removing 3'-blocking fragments of deoxyribose that prevent DNA repair synthesis. Two enzymes were found in a v...

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Detalhes bibliográficos
Main Authors: Chen, D S, Herman, T, Demple, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329046/
https://ncbi.nlm.nih.gov/pubmed/1719484
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