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MeCP2 deficiency disrupts axonal guidance, fasciculation, and targeting by altering Semaphorin 3F function
Rett Syndrome (RTT) is an autism spectrum disorder that results from mutations in the transcriptional regulator methyl-CpG binding protein 2 (MECP2). In the present work, we demonstrate that MeCP2 deficiency disrupts the establishment of neural connections before synaptogenesis. Using both in vitro...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3290450/ https://ncbi.nlm.nih.gov/pubmed/19628041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2009.07.009 |
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