Natural killer cell-produced IFN-γ and TNF-α induce target cell cytolysis through up-regulation of ICAM-1

NK cells control tumor and virus-infected cells through releasing cytotoxic granules and proinflammatory cytokines. IFN-γ and TNF-α secretions and cytotoxicity are regarded as two distinct functions of NK cells with little synergy in between as results of early association of the two functions with...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Ruipeng, Jaw, Jessica J., Stutzman, Nicole C., Zou, Zhongcheng, Sun, Peter D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Leukocyte Biology 2012
Konular:
Inflammation, Extracellular Mediators, & Effector Molecules
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290424/
https://ncbi.nlm.nih.gov/pubmed/22045868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0611308
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