Estradiol down regulates the binding activity of an avian vitellogenin gene repressor (MDBP-2) and triggers a gradual demethylation of the mCpG pair of its DNA binding site.

Eitemau Tebyg

• Genomic sequencing and in vivo footprinting of an expression-specific DNase I-hypersensitive site of avian vitellogenin II promoter reveal a demethylation of a mCpG and a change in specific interactions of proteins with DNA.
  gan: Saluz, H P, et al.
  Cyhoeddwyd: (1988)
• Interaction of two nonhistone proteins with the estradiol response element of the avian vitellogenin gene modulates the binding of estradiol-receptor complex.
  gan: Feavers, I M, et al.
  Cyhoeddwyd: (1987)
• Genomic sequencing reveals a positive correlation between the kinetics of strand-specific DNA demethylation of the overlapping estradiol/glucocorticoid-receptor binding sites and the rate of avian vitellogenin mRNA synthesis.
  gan: Saluz, H P, et al.
  Cyhoeddwyd: (1986)
• In vivo estradiol-dependent dephosphorylation of the repressor MDBP-2-H1 correlates with the loss of in vitro preferential binding to methylated DNA.
  gan: Bruhat, A, et al.
  Cyhoeddwyd: (1995)
• An avian 40 KDa nucleoprotein binds preferentially to a promoter sequence containing one single pair of methylated CpG.
  gan: Pawlak, A, et al.
  Cyhoeddwyd: (1991)