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Selectively targeting Mcl-1 for the treatment of acute myelogenous leukemia and solid tumors
Bcl-2, Bcl-x(L), Mcl-1, and A1 are the predominant anti-apoptotic members of the Bcl-2 family in somatic cells. Malignant B lymphocytes are critically dependent on Bcl-2 or Bcl-x(L) for survival. In contrast, a new study by Glaser and colleagues in the January 15, 2012, issue of Genes & Developm...
Bewaard in:
| Hoofdauteurs: | , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Cold Spring Harbor Laboratory Press
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289878/ https://ncbi.nlm.nih.gov/pubmed/22345513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.186189.111 |
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