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Pharmacological and Therapeutic Effects of A(3) Adenosine Receptor (A(3)AR) Agonists

The G(i)-coupled A(3) adenosine receptor (A(3)AR) mediates anti-inflammatory, anticancer and anti-ischemic protective effects. The receptor is overexpressed in inflammatory and cancer cells, while low expression is found in normal cells, rendering the A(3)AR as a potential therapeutic target. Highly...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fishman, Pnina, Bar-Yehuda, Sara, Liang, Bruce T., Jacobson, Kenneth A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289754/
https://ncbi.nlm.nih.gov/pubmed/22033198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2011.10.007
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