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CF101, An Agonist to the A(3) Adenosine Receptor, Enhances the Chemotherapeutic Effect of 5-Fluorouracil in a Colon Carcinoma Murine Model

NF-κB and the upstream kinase PKB/Akt are highly expressed in chemoresistance tumor cells and may hamper the apoptotic pathway. CF101, a specific agonist to the A(3) adenosine receptor, inhibits the development of colon carcinoma growth in cell cultures and xenograft murine models. Because CF101 has...

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Detalhes bibliográficos
Main Authors: Bar-Yehuda, Sara, Madi, Lea, Silberman, Daniel, Gery, Slosman, Shkapenuk, Maya, Fishman, Pnina
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1490317/
https://ncbi.nlm.nih.gov/pubmed/15720820
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