Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A(3 )adenosine receptor expression

Methotrexate (MTX) exerts an anti-inflammatory effect via its metabolite adenosine, which activates adenosine receptors. The A(3 )adenosine receptor (A(3)AR) was found to be highly expressed in inflammatory tissues and peripheral blood mononuclear cells (PBMCs) of rats with adjuvant-induced arthriti...

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Bibliografski detalji
Glavni autori: Ochaion, Avivit, Bar-Yehuda, Sara, Cohn, Shira, Del Valle, Luis, Perez-Liz, Georginia, Madi, Lea, Barer, Faina, Farbstein, Motti, Fishman-Furman, Sari, Reitblat, Tatiana, Reitblat, Alexander, Amital, Howard, Levi, Yair, Molad, Yair, Mader, Reuven, Tishler, Moshe, Langevitz, Pnina, Zabutti, Alexander, Fishman, Pnina
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2006
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794513/
https://ncbi.nlm.nih.gov/pubmed/17101059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2078
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