Effect of 5-methylcytosine on the stability of triple-stranded DNA--a thermodynamic study.

We have previously shown that the pyrimidine oligonucleotide 5'CTTCCTCCTCT (Y11) recognizes the double-helical stem of hairpin 5'GAAGGAGGAGA-T4-TCTCCTCCTTC (h26) by triple-helix formation (1). In this paper, we report the effect on triplex formation of substituting the cytosine residues of...

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Bibliographic Details
Main Authors: Xodo, L E, Manzini, G, Quadrifoglio, F, van der Marel, G A, van Boom, J H
Format: Artigo
Language:Inglês
Published: 1991
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC328967/
https://ncbi.nlm.nih.gov/pubmed/1945840
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