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The RNA Polymerase PB2 Subunit of Influenza A/HongKong/156/1997 (H5N1) Restrict the Replication of Reassortant Ribonucleoprotein Complexes

BACKGROUND: Genetic reassortment plays a critical role in the generation of pandemic strains of influenza virus. The influenza virus RNA polymerase, composed of PB1, PB2 and PA subunits, has been suggested to influence the efficiency of genetic reassortment. However, the role of the RNA polymerase i...

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Detalhes bibliográficos
Main Authors: Nakazono, Yoko, Hara, Koyu, Kashiwagi, Takahito, Hamada, Nobuyuki, Watanabe, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289661/
https://ncbi.nlm.nih.gov/pubmed/22389716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032634
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