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Gene Deletion of nos2 Protects Against Manganese-Induced Neurological Dysfunction in Juvenile Mice

The mechanisms underlying cognitive and neurobehavioral abnormalities associated with childhood exposure to manganese (Mn) are not well understood but may be influenced by neuroinflammatory activation of microglia and astrocytes that results in nitrosative stress due to expression of inducible nitri...

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Detalhes bibliográficos
Main Authors: Streifel, Karin M., Moreno, Julie A., Hanneman, William H., Legare, Marie E., Tjalkens, Ronald B.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289496/
https://ncbi.nlm.nih.gov/pubmed/22174044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr335
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