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mGluR6 deletion renders the TRPM1 channel in retina inactive
In darkness, glutamate released from photoreceptors activates the metabotropic glutamate receptor 6 (mGluR6) on retinal ON bipolar cells. This activates the G protein G(o), which then closes transient receptor potential melastatin 1 (TRPM1) channels, leading to cells' hyperpolarization. It has...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289472/ https://ncbi.nlm.nih.gov/pubmed/22131384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00933.2011 |
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