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Optimizing ring assembly reveals the strength of weak interactions

Most cellular processes rely on large multiprotein complexes that must assemble into a well-defined quaternary structure in order to function. A number of prominent examples, including the 20S core particle of the proteasome and the AAA+ family of ATPases, contain ring-like structures. Developing an...

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Détails bibliographiques
Auteurs principaux: Deeds, Eric J., Bachman, John A., Fontana, Walter
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289332/
https://ncbi.nlm.nih.gov/pubmed/22308356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113095109
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