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Nadph oxidase regulates alveolar epithelial sodium channel activity and lung fluid balance in vivo via O(2)(−) signaling

To define roles for reactive oxygen species (ROS) and epithelial sodium channel (ENaC) in maintaining lung fluid balance in vivo, we used two novel whole animal imaging approaches. Live X-ray fluoroscopy enabled quantification of air space fluid content of C57BL/6J mouse lungs challenged by intratra...

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Main Authors: Goodson, Preston, Kumar, Amrita, Jain, Lucky, Kundu, Kousik, Murthy, Niren, Koval, Michael, Helms, My N.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289267/
https://ncbi.nlm.nih.gov/pubmed/22160304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00260.2011
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