Rac1-mediated NADPH oxidase release of O(2)(−) regulates epithelial sodium channel activity in the alveolar epithelium

We examine whether alveolar cells can control release of O(2)(−) through regulated NADPH oxidase (NOX) 2 (NOX2) activity to maintain lung fluid homeostasis. Using FACS to purify alveolar epithelial cells, we show that type 1 cells robustly express each of the critical NOX components that catalyze th...

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Bibliografiska uppgifter
Huvudupphovsmän: Takemura, Yoshizumi, Goodson, Preston, Bao, Hui Fang, Jain, Lucky, Helms, My N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2010
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2853346/
https://ncbi.nlm.nih.gov/pubmed/20097736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00230.2009
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