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Rac1-mediated NADPH oxidase release of O(2)(−) regulates epithelial sodium channel activity in the alveolar epithelium
We examine whether alveolar cells can control release of O(2)(−) through regulated NADPH oxidase (NOX) 2 (NOX2) activity to maintain lung fluid homeostasis. Using FACS to purify alveolar epithelial cells, we show that type 1 cells robustly express each of the critical NOX components that catalyze th...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Physiological Society
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2853346/ https://ncbi.nlm.nih.gov/pubmed/20097736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00230.2009 |
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