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Single Chain MHC I trimer-based DNA vaccines for protection against Listeria monocytogenes infection
To circumvent limitations of poor antigen presentation and immunogenicity of DNA vaccines that target induction of CD8(+) T cell immunity, we have generated single chain MHC I trimers (MHC I SCTs) composed of a single polypeptide chain with a linear composition of antigenic peptide, β2-microglobulin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288962/ https://ncbi.nlm.nih.gov/pubmed/22285270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2012.01.012 |
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