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Single-Chain HLA-A2 MHC Trimers That Incorporate an Immundominant Peptide Elicit Protective T Cell Immunity against Lethal West Nile Virus Infection

The generation of a robust CD8(+)T cell response is an ongoing challenge for the development of DNA vaccines. One problem encountered with classical DNA plasmid immunization is that peptides produced are noncovalently and transiently associated with MHC class I molecules and thus may not durably sti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kim, Sojung, Li, Lijin, McMurtrey, Curtis P., Hildebrand, William H., Weidanz, Jon A., Gillanders, William E., Diamond, Michael S., Hansen, Ted H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628725/
https://ncbi.nlm.nih.gov/pubmed/20212098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903955
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