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PTTG induces EMT through integrin AlphaV Beta3-focal adhesion kinase signaling in lung cancer cells

Pituitary tumor transforming gene (PTTG) is a well-studied oncogene for its role in tumorigenesis and serves as a marker of malignancy in several cancer types including lung. In the present study, we defined the role of PTTG in actin cytoskeleton remodeling, cell migration and induction of epithelia...

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Bibliographic Details
Main Authors: Shah, Parag P., Fong, Miranda Y., Kakar, Sham S.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288952/
https://ncbi.nlm.nih.gov/pubmed/22081074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.488
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