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Dual Inhibition of AlphaV Integrins and Src Kinase Activity as A Combination Therapy Strategy for Colorectal Cancer
OBJECTIVE: Src and α(V) integrins are both important for tumor growth and angiogenesis. They are interconnected and responsible for important features of the tumor phenotype including invasiveness, metastasis, angiogenesis and resistance to apoptosis. This study examines whether combinational inhibi...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3828660/ https://ncbi.nlm.nih.gov/pubmed/23275294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e32835d29fd |
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