Nanoparticle Migration and Delivery of Paclitaxel to Regional Lymph Nodes in a Large Animal Model

BACKGROUND: To demonstrate feasibility of migration and in situ chemotherapy delivery to regional lymph nodes (LN) in a large animal model using an expansile polymer nanoparticle (eNP) delivery system. STUDY DESIGN: Dual-labeled 50 nm and 100 nm eNP were prepared by encapsulating an IR-813 near-infr...

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Main Authors: Khullar, Onkar V, Griset, Aaron P, Gibbs-Strauss, Summer L, Chirieac, Lucian R, Zubris, Kimberly AV, Frangioni, John V, Grinstaff, Mark W, Colson, Yolonda L
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288886/
https://ncbi.nlm.nih.gov/pubmed/22225645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jamcollsurg.2011.11.006
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