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Differential regulation of primary and memory CD8 T cell immune responses by diacylglycerol kinases
The manipulation of signals downstream of the T cell receptor (TCR) can have profound consequences for T cell development, function, and homeostasis. Diacylglycerol (DAG) produced following TCR stimulation functions as a secondary messenger and mediates the signaling to Ras-MEK-Erk and NF-κB pathway...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288785/ https://ncbi.nlm.nih.gov/pubmed/22271650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102265 |
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