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The IKKα-dependent NF-κB p52/RelB non-canonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1
HMGB1 is a chromatin architectural protein that is released by dead or damaged cells at sites of tissue injury. Extracellular HMGB1 functions as a pro-inflammatory cytokine and chemoattractant for immune effector and progenitor cells. Previously, we have shown that the IKKβ and IKKα-dependent NF-κB...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288724/ https://ncbi.nlm.nih.gov/pubmed/22287708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102454 |
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