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Ultra-low Dose of Mycobacterium tuberculosis Aerosol Creates Partial Infection in Mice
A murine low-dose (LD) aerosol model is commonly used to test tuberculosis vaccines. Doses of 50-400 CFU (24-hour lung CFU) infect 100% of exposed mice. The LD model measures progression from infection to disease based on organ CFU at defined time points. To mimic natural exposure, we exposed mice t...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288716/ https://ncbi.nlm.nih.gov/pubmed/22197183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2011.11.007 |
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