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Ultra-low Dose Aerosol Infection of Mice with Mycobacterium tuberculosis More Closely Models Human Tuberculosis

Tuberculosis (TB) is a heterogeneous disease manifesting in a subset of individuals infected with aerosolized Mycobacterium tuberculosis (Mtb). Unlike human TB, murine infection results in uniformly high lung bacterial burdens and poorly organized granulomas. To develop a TB model that more closely...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Plumlee, Courtney R., Duffy, Fergal J., Gern, Benjamin H., Delahaye, Jared L., Cohen, Sara B., Stoltzfus, Caleb R., Rustad, Tige R., Hansen, Scott G., Axthelm, Michael K., Picker, Louis J., Aitchison, John D., Sherman, David R., Ganusov, Vitaly V., Gerner, Michael Y., Zak, Daniel E., Urdahl, Kevin B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7854984/
https://ncbi.nlm.nih.gov/pubmed/33142108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2020.10.003
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