The nicotine metabolite, cotinine, attenuates glutamate (NMDA) antagonist-related effects on the performance of the five choice serial reaction time task (5C-SRTT) in rats

Cotinine, the most predominant metabolite of nicotine in mammalian species, has a pharmacological half-life that greatly exceeds its precursor. However, until recently, relatively few studies had been conducted to systematically characterize the behavioral pharmacology of cotinine. Our previous work...

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Main Authors: Terry, Alvin V., Buccafusco, Jerry J., Schade, R. Foster, Vandenhuerk, Leah, Callahan, Patrick M., Beck, Wayne D., Hutchings, Elizabeth J., Chapman, James M., Li, Pei, Bartlett, Michael G.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288613/
https://ncbi.nlm.nih.gov/pubmed/22244928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.12.043
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