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Effects of mitochondrial poisons on the neuropathic pain produced by the chemotherapeutic agents, paclitaxel and oxaliplatin

The dose-limiting side-effect of taxane, platinum-complex, and other kinds of anti-cancer drugs is a chronic, distal, bilaterally symmetrical, sensory peripheral neuropathy that is often accompanied by neuropathic pain. Work with animal models of these conditions suggests that the neuropathy is a co...

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Detalhes bibliográficos
Main Authors: Xiao, Wen Hua, Bennett, Gary J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288606/
https://ncbi.nlm.nih.gov/pubmed/22244441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2011.12.011
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