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Olesoxime (cholest-4-en-3-one, oxime): Analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel

Olesoxime is a small cholesterol-like molecule that was discovered in a screening program aimed at finding treatment for amyotrophic lateral sclerosis and other diseases where motor neurons degenerate. In addition to its neuroprotective and pro-regenerative effects on motor neurons in vitro and in v...

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Bibliografske podrobnosti
Main Authors: Xiao, Wen Hua, Zheng, Felix Y., Bennett, Gary J., Bordet, Thierry, Pruss, Rebecca M.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787910/
https://ncbi.nlm.nih.gov/pubmed/19833436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2009.09.006
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