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α–Synuclein Increases the Cellular Level of Phospholipase Cβ1
α-Synuclein is a conserved protein that is a key component in neurodegenerative plaques [1, 2]. α-Synuclein binds strongly to phospholipase Cβ (PLCβ) and promotes Ca(2+) release in cells. Here, we show that expression of α-synuclein increases the cellular level of PLCβ1 in two neuronal cell lines: P...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288587/ https://ncbi.nlm.nih.gov/pubmed/22286107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.01.007 |
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