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Drosophila Epsin’s role in Notch ligand cells requires three Epsin protein functions: the lipid binding function of the ENTH domain, a single Ubiquitin interaction motif, and a subset of the C-terminal protein binding modules

Epsin is an endocytic protein that binds Clathrin, the plasma membrane, Ubiquitin, and also a variety of other endocytic proteins through well-characterized motifs. Although Epsin is a general endocytic factor, genetic analysis in Drosophila and mice revealed that Epsin is essential specifically for...

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Bibliografiske detaljer
Main Authors: Xie, Xuanhua, Cho, Bomsoo, Fischer, Janice A.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288543/
https://ncbi.nlm.nih.gov/pubmed/22265678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.01.004
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