The Functions of Auxilin and Rab11 in Drosophila Suggest That the Fundamental Role of Ligand Endocytosis in Notch Signaling Cells Is Not Recycling

Notch signaling requires ligand internalization by the signal sending cells. Two endocytic proteins, epsin and auxilin, are essential for ligand internalization and signaling. Epsin promotes clathrin-coated vesicle formation, and auxilin uncoats clathrin from newly internalized vesicles. Two hypothe...

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Détails bibliographiques
Auteurs principaux: Banks, Susan M. L., Cho, Bomsoo, Eun, Suk Ho, Lee, Ji-Hoon, Windler, Sarah L., Xie, Xuanhua, Bilder, David, Fischer, Janice A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2011
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063240/
https://ncbi.nlm.nih.gov/pubmed/21448287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018259
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