BMP2 signals loss of epithelial character in epicardial cells but requires the Type III TGFβ receptor to promote invasion

Coronary vessel development depends on a subpopulation of epicardial cells that undergo epithelial to mesenchymal transformation (EMT) and invade the subepicardial space and myocardium. These cells form the smooth muscle of the vessels and fibroblasts, but the mechanisms that regulate these processe...

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Autores principales: Hill, Cynthia R., Sanchez, Nora S., Love, Joseph D., Arrieta, Julian A., Hong, Charles C., Brown, Christopher B., Austin, Anita F., Barnett, Joey V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288519/
https://ncbi.nlm.nih.gov/pubmed/22237159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.12.022
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