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Single-cell analysis reveals that noncoding RNAs contribute to clonal heterogeneity by modulating transcription factor recruitment

Mechanisms through which long intergenic noncoding RNAs (ncRNAs) exert regulatory effects on eukaryotic biological processes remain largely elusive. Most studies of these phenomena rely on methods that measure average behaviors in cell populations, lacking resolution to observe the effects of ncRNA...

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Autors principals: Bumgarner, Stacie L., Neuert, Gregor, Voight, Benjamin F., Symbor-Nagrabska, Anna, Grisafi, Paula, van Oudenaarden, Alexander, Fink, Gerald R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288511/
https://ncbi.nlm.nih.gov/pubmed/22264825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.11.029
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