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Identification of Rv0535 as methylthioadenosine phosphorylase from Mycobacterium tuberculosis

5′-methylthioadenosine (MTA) is a natural purine that is metabolized by methylthioadenosine phosphorylase (MTAP, E.C 2.4.2.28) in Eukarya and Archaea but generally not in bacteria. In this work, Rv0535, which has been annotated as a probable MTAP in M. tuberculosis, was expressed in and purified fro...

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Detalhes bibliográficos
Main Authors: Buckoreelall, Kajal, Sun, Yanjie, Hobrath, Judith V., Wilson, Landon, Parker, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288397/
https://ncbi.nlm.nih.gov/pubmed/22225784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tube.2011.11.010
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