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Resistance to HSV-1 Infection in the Epithelium Resides with the Novel Innate Sensor, IFI-16
Toll-like receptors (TLRs) are innate sentinels required for clearance of bacterial and fungal infections of the cornea, but their role in viral immunity is currently unknown. We report TLR signaling is expendable in HSV-1 containment as depicted by plaque assays of knockout mice (MyD88(−/−), Trif(−...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288395/ https://ncbi.nlm.nih.gov/pubmed/22236996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2011.63 |
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