Common Genetic Variation in the 3-BCL11B Gene Desert Is Associated With Carotid-Femoral Pulse Wave Velocity and Excess Cardiovascular Disease Risk The AortaGen Consortium

BACKGROUND: Carotid-femoral pulse wave velocity (CFPWV) is a heritable measure of aortic stiffness that is strongly associated with increased risk for major cardiovascular disease events. METHODS AND RESULTS: We conducted a meta-analysis of genome-wide association data in 9 community-based European...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mitchell, Gary F., Verwoert, Germaine C., Tarasov, Kirill V., Isaacs, Aaron, Smith, Albert V., Yasmin, Rietzschel, Ernst R., Tanaka, Toshiko, Liu, Yongmei, Parsa, Afshin, Najjar, Samer S., O’Shaughnessy, Kevin M., Sigurdsson, Sigurdur, De Buyzere, Marc L., Larson, Martin G., Sie, Mark P.S., Andrews, Jeanette S., Post, Wendy S., Mattace-Raso, Francesco U.S., McEniery, Carmel M., Eiriksdottir, Gudny, Segers, Patrick, Vasan, Ramachandran S., van Rijn, Marie Josee E., Howard, Timothy D., McArdle, Patrick F., Dehghan, Abbas, Jewell, Elizabeth, Newhouse, Stephen J., Bekaert, Sofie, Hamburg, Naomi M., Newman, Anne B., Hofman, Albert, Scuteri, Angelo, De Bacquer, Dirk, Ikram, Mohammad Arfan, Psaty, Bruce, Fuchsberger, Christian, Olden, Matthias, Wain, Louise V., Elliott, Paul, Smith, Nicholas L., Felix, Janine F., Erdmann, Jeanette, Vita, Joseph A., Sutton-Tyrrell, Kim, Sijbrands, Eric J.G., Sanna, Serena, Launer, Lenore J., De Meyer, Tim, Johnson, Andrew D., Schut, Anna F.C., Herrington, David M., Rivadeneira, Fernando, Uda, Manuela, Wilkinson, Ian B., Aspelund, Thor, Gillebert, Thierry C., Van Bortel, Luc, Benjamin, Emelia J., Oostra, Ben A., Ding, Jingzhong, Gibson, Quince, Uitterlinden, André G., Abecasis, Gonçalo R., Cockcroft, John R., Gudnason, Vilmundur, De Backer, Guy G., Ferrucci, Luigi, Harris, Tamara B., Shuldiner, Alan R., van Duijn, Cornelia M., Levy, Daniel, Lakatta, Edward G., Witteman, Jacqueline C.M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288392/
https://ncbi.nlm.nih.gov/pubmed/22068335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.111.959817
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