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Towards an understanding of the role of p53 in Adrenocortical Carcinogenesis
Adrenocortical carcinoma (ACC) is recognized to be a component tumor of the Li Fraumeni Syndrome (LFS), a familial cancer predisposition resulting from germline mutations in the p53 tumor-suppressor. p53 activity is tightly regulated by multiple post-translational mechanisms, disruption of which may...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288384/ https://ncbi.nlm.nih.gov/pubmed/21930187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2011.09.010 |
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