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Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions
Myosin IIIA (MYO3A) targets actin protrusion tips using a motility mechanism dependent on both motor and tail actin-binding activity [1]. We show that myosin IIIB (MYO3B) lacks tail actin-binding activity and is unable to target COS7 cell filopodia tips, yet is somehow able to target stereocilia tip...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288355/ https://ncbi.nlm.nih.gov/pubmed/22264607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2011.12.053 |
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