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Automated RNA Tertiary Structure Prediction from Secondary Structure and Low-Resolution Restraints

A novel protocol for all-atom RNA tertiary structure prediction is presented that employs restrained molecular mechanics and simulated annealing. The restraints are from secondary structure, co-variation analysis, coaxial stacking predictions for helices in junctions, and, when available, cross-link...

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Detalhes bibliográficos
Main Authors: Seetin, Matthew G., Mathews, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288334/
https://ncbi.nlm.nih.gov/pubmed/21509787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcc.21806
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